Validation of the Gender-Equity Model for liver Allocation (GEMA) in Spain: a nationwide cohort study

Research areas:

• Uncategorized

Year:

2024

Type of Publication:

In Proceedings

Authors:

• Rodríguez-Perálvez, Manuel
• de la Rosa, Gloria
• Gómez-Orellana, Antonio Manuel
• Sancho, Victoria Aguilera
• Pascual-Vicente, Teresa
• Pereira, Sheila
• Ortiz, María Luisa
• Pagano, Giulia
• Suárez, Francisco
• González-Grande, Rocio
• Cachero, Alba
• Tomé, Santiago
• Valbuena, Mónica Barreales
• Martin-Mateos, Rosa
• Pascual, Sonia
• Cristóbal, Mario Romero
• Bilbao, Itxarone
• Martin, Carmen Alonso
• Oton, Elena
• Dieguez, Maria Luisa Gonzalez
• Aguilar, María Dolores Espinosa
• Arias, Ana
• Blanco, Gerar
• Perez, Sara Lorente
• Cuadrado, Antonio
• García, Amaya Redín
• Cano, Clara Sánchez
• Franco, Carmen Cepeda
• Pons, Jose Antonio
• Colmenero, Jordi
• Ferreiro, Alejandra Otero
• Aretxabaleta, Nerea Hernández
• Moreno, Sarai Romero
• Soler, Maria Rodriguez
• Hervás-Martínez, César
• Gastaca, Mikel

Volume:

30

Book title:

ILTS Annual Congress 2024

Pages:

1-309

Month:

Septiembre

BibTex:

@conference{GEMA_OP14_2024, author = "Manuel Rodr{\'i}guez-Per{\'a}lvez and de la Rosa, Gloria and Antonio Manuel G{\'o}mez-Orellana and Victoria Aguilera Sancho and Teresa Pascual-Vicente and Sheila Pereira and Mar{\'i}a Luisa Ortiz and Giulia Pagano and Francisco Su{\'a}rez and Rocio Gonz{\'a}lez-Grande and Alba Cachero and Santiago Tom{\'e} and M{\'o}nica Barreales Valbuena and Rosa Martin-Mateos and Sonia Pascual and Mario Romero Crist{\'o}bal and Itxarone Bilbao and Carmen Alonso Martin and Elena Oton and Maria Luisa Gonzalez Dieguez and Mar{\'i}a Dolores Espinosa Aguilar and Ana Arias and Gerar Blanco and Sara Lorente Perez and Antonio Cuadrado and Amaya Red{\'i}n Garc{\'i}a and Clara S{\'a}nchez Cano and Carmen Cepeda Franco and Jose Antonio Pons and Jordi Colmenero and Alejandra Otero Ferreiro and Nerea Hern{\'a}ndez Aretxabaleta and Sarai Romero Moreno and Maria Rodriguez Soler and C{\'e}sar Herv{\'a}s-Mart{\'i}nez and Mikel Gastaca", abstract = "Background: The Gender-Equity model for liver Allocation corrected by sodium (GEMA-Na) may save a meaningful number of lives while palliating gender disparities among liver transplant (LT) candidates (PMID 36528041). We aimed to validate its performance in Spain, where waiting time for LT is reduced. Methods: Nationwide cohort study including adult candidates for elective LT from 25 centers in Spain (2014-2021). The primary outcome was mortality or delisting for sickness with right-censoring at 90 days. The GEMA-Na score was calculated according to the published formula available at: http://gema-transplant.com/. The discrimination of GEMA-Na was assessed by the Harrel’s c-statistic (Hc) and compared with MELD-Na, and MELD 3.0.", awards = "(JCR: 5.1)", booktitle = "ILTS Annual Congress 2024", comments = "(JCR: 5.1)", month = "Septiembre", note = "(JCR: 5.1)", pages = "1--309", title = "{V}alidation of the {G}ender-{E}quity {M}odel for liver {A}llocation ({GEMA}) in {S}pain: a nationwide cohort study", url = "journals.lww.com/lt/citation/2024/09001/ilts_annual_congress_2024_abstracts.1.aspx", volume = "30", year = "2024", }

Note:

(JCR: 5.1)

Abstract:

Background: The Gender-Equity model for liver Allocation corrected by sodium (GEMA-Na) may save a meaningful number of lives while palliating gender disparities among liver transplant (LT) candidates (PMID 36528041). We aimed to validate its performance in Spain, where waiting time for LT is reduced. Methods: Nationwide cohort study including adult candidates for elective LT from 25 centers in Spain (2014-2021). The primary outcome was mortality or delisting for sickness with right-censoring at 90 days. The GEMA-Na score was calculated according to the published formula available at: http://gema-transplant.com/. The discrimination of GEMA-Na was assessed by the Harrel’s c-statistic (Hc) and compared with MELD-Na, and MELD 3.0.

Comments:

(JCR: 5.1)